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It is a deliberate choice by some providers to reduce the incidence of nausea, vomiting, and other gastrointestinal side effects that cause many patients to abandon treatment entirely

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MS reduced the expression of NeuroD1 more significantly than in HG-HL-induced -cells and failed to restore Foxo1 mRNA or the protein levels of PDX-1 and FOXO1 (Figure 5B)